Sergi Padilla-Parra

Principal Investigator
Dr. Sergi Padilla-Parra

 My laboratory is focused on the development of fluorescence imaging approaches capable of showing the spatial and temporal regulation of protein-protein interactions and/or enzymatic activity inside living cells and animals. We are developing novel methodological approaches for Lifetime Imaging (FLIM) and fluorescence cross-correlation (FCCS) techniques. We are particularly interested in improving the time resolution for FRET-FLIM acquisitions by using non-fitting approaches and also developing ‘artifact free’ FCCS techniques.
 
This technology allows us to detect and characterize the cell factors involved during Influenza infection, and compare their spatio-temporal activity with other enveloped viruses and/or pseudoviruses known to enter the cell through endocytosis (like Vesicular Stomatitis Virus (VSV), Avian Sarcoma and Leukosis Virus (ASLV) and Vaccinia Virus (VV)).

To find out more, please visit my research pages or send me an email.

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