Nynke Dekker
Professor
Professor Nynke Dekker at Oxford conducts pioneering single-molecule biophysics research aimed at understanding how DNA, RNA and their associated molecular motors function in real time. Her lab combines high-precision techniques such as single-molecule fluorescence, magnetic and optical tweezers, and integrated force-fluorescence spectroscopy to visualize the dynamics of replisome assembly, replication fork progression, and chromatin interactions. They explore replication in eukaryotes, bacteria and viruses, including how accessory proteins, nucleosomes, and obstacles impact fidelity. Her work bridges physics, biochemistry and molecular biology to yield mechanistic insight into replication and its dysregulation in disease.
